Asbestos Causing Cancer Mechanism

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Asbestos and other fibers induce predominantly two types of cancers: A mechanism for cell transformation, which is dependent on fiber dimension, has been .Cytogenetic and molecular stu.s of asbestos-related cancers indicate that inactivation or loss of multiple tumor suppressor genes occurs during lung cancer development. Furthermore, asbestos fibers may influence the carcinogenic process by inducing cell proliferation, free radicals, or other promotional mechanisms..The presence of asbestos fibers in the lungs sets off a variety of responses leading to inflammation, cell, and tissue damage, which can lead to malignant and non-malignant diseases. The mechanisms by which asbestos causes disease are not fully understood. Other cell-mediated mechanisms especially inflammation ..Learn about the mechanisms Of Asbestos Carcinogenesis on this page. Identify Mechanisms of Asbestos Carcinogenesis and Biomarkers for Early Detection Carbone M, Yang H, Pass HI, Krausz T, Testa JR, Gaudino G. Bap1 and cancer..

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